This page presents my former research projects
PullCoVapart – Pull the Covid-19 replicative catalytic core apart
This is an interdisciplinary project (with two laboratories in Marseille; AFMB and LIS, funded by ANR and INSERM), combining methods in artificial intelligence with protein biochemistry to propose therapeutic options to Covid-19. The three main objectives of the project are to (1) reconstitute, in vitro, the replication complex of the COVID-19; (2) model and simulate its replication activity in silico and finally (3) compare the in silico results with the in vitro experimentations to validate them (or not).
The most important expected contribution in this project is the proposal of a methodology to « translate » hybrid conceptual models (ontologies and reasoning rules) into DEVS simulation models.
The website of the project is http://pullcovapart.projets.litislab.fr/
Semantic Technologies for Industry 4.0
Several axes appear in these works (click here to access a summary poster):
- One of the first axis concerns the HALFBACK project, whose funding was confirmed on January 31st 2017. This project is about the creation of highly available intelligent factories in the cloud and concerns the application of semantic technologies for the proposal of intelligent maintenance plans.
- A new axis has been launched in October 2017, with the STEaMINg (Semantic Time Evolving Models for Industry 4.0) project, funded by the Normandy region. In an Industry 4.0 framework, beyond the need to interpret data generated by sensors that monitor processes, the necessity for real-time adaptation to unforeseen events or for predictive monitoring imply the need to manage knowledge models that evolve over time. In this project, we will, therefore, focus on understanding the knowledge evolution over time and its distributed management, in an industrial framework, with different case studies.
- Another axis is focused on the Formalization of the touch control process of a product (Felicity project). The proposed research work aims to study the tactile perception. Indeed, in the context of quality control, it is this type of perception that is more requested, the controller generally operates exploratory movements with his hand to control the product. Therefore in this research project, we will focus on the development of a hardware and software IDA (intelligent data analysis) platform capable of supporting various mechanisms for analysis of unstructured data from sensor networks. This scan task involves an artificial perception process designed to abstract the characteristics observed by sensors on domain concepts that describe the object of study. A key aspect of this project is to define a strategy for anchoring symbols to build interpretations at different levels of abstraction. These works are led in the framework of a co-supervised PhD industrial (CIFRE) thesis with the SYMME laboratory and INEVA.
- The last and oldest axis was initially focused on the formalisation of IDM (Inventive Design Methodology) that is applied by companies to improve their R&D activities. A knowledge manager was developed to assist the IDM experts during their activities. Indeed, during a new study, experts are brought to work with various models at different levels of abstraction. The knowledge manager suggests the experts the use of the relevant knowledge sources (barely formalised in natural language), consistent with the level of abstraction of the model they are building. The manager is also able to complete the rest of the models, by exploiting the semantic links obtained among the different knowledge sources. We are currently working in the capitalisation of experience of past studies to improve the whole inventive process, by the application of successful results to new cases that can belong to a completely different domain. Case-Based Reasoning and SOEDS and DDNA technologies will be used with this aim. These works are led in the framework of a co-supervised PhD thesis with the LGECO laboratory.
Formalisation of Complex Biomolecular Networks
The « transittability » of a complex biomolecular network expresses the idea of steering a biomolecular network from an undesired condition (generally associated with a disease) to a desired, hopefully, healthy state. In these PhD works, we are interested in the formalisation of these complex biomolecular networks and in the proposal of a platform based on semantic technologies for the optimization of the transittability of these biomolecular networks. These works are led in the framework a PhD thesis under a joint supervision agreement with the University of Tunisia and its LARODEC laboratory and also concern a collaboration with the CSTB team of ICube
Semantic Region Labeling for Remote Sensing Image Interpretation
The increasing availability of High Spatial Resolution satellite images is an opportunity to characterize and identify urban objects. Image analyses methods using object-based approaches based on the use of domain knowledge are necessary to classify data. A major issue in these approaches is domain knowledge formalization and exploitation. The use of formal ontologies seems a judicious choice to deal with these issues. Therefore, the aim of these works is to highlight the benefits in the use of a thematic ontology for automatic regions labelling. Description logics (DL) are being used to exploit the knowledge in the ontologies and develop software tools to assist the automatic labelling of satellite images.
In the framework of these works, I have participated in the COCLICO project funded by the French National Research Agency.
Semantic Technologies for Improving the Readability and the Comprehensibility of Strasbourg University
In the framework of the IDEX (excellence initiative) called « Complex Identities » I have worked with the Faculty of Arts of Strasbourg University to try and provide the means to understand the complexity of this institution, with the use of semantic technologies. This collaboration is described in number 27 of the #Savoir(s) journal of May 2016.